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Evaluation and Management of Seizures and Status Epilepticus

The infiltration of immune cells such as macrophages, neutrophils, mast cells, B cells, T cells, NKT cells within the adipose tissue, coupled with the overproduction of inflammatory mediators and adipokines (e.g., leptin and lipocalin), adipocyte-derived MCP-1 and hypertrophy of visceral adipocytes, leads to hypoxia, autophagy, and apoptosis (130)

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Furthermore, the timing and consistency of the exercise tests could have introduced variability

Autophagy removes damaged or junk organelles in cells (Ashrafi and Schwarz, 2013)